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Molecular biology in medicinal chemi...

Dingermann, Theodor.

Molecular biology in medicinal chemistry /

紀錄類型:	書目-語言資料,印刷品 : 單行本
正題名/作者:	Molecular biology in medicinal chemistry // edited by Th. Dingermann, D. Steinhilber and G. Folkers.
其他作者:	Dingermann, Theodor.
出版者:	Weinheim :Wiley-VCH, : 2004.,
面頁冊數:	xxi, 413 p. :ill. ; : 24 cm.;
叢書名:	Methods and principles in medicinal chemistry ;
標題:	Molecular biology. -
電子資源:	http://www.loc.gov/catdir/toc/wiley051/2004351376.html
ISBN:	3527304312 (bound) :

Molecular biology in medicinal chemistry /
Molecular biology in medicinal chemistry /edited by Th. Dingermann, D. Steinhilber and G. Folkers. - 1. Aufl. - Weinheim :Wiley-VCH,2004. - xxi, 413 p. :ill. ;24 cm. - Methods and principles in medicinal chemistry ;v. 21.

Includes bibliographical references and index.

Cellular assays in drug discovery -- Gene knockout models -- Reporter gene assay systems for the investigation of GPCRs -- From the human genome to new drugs: The potential of orphan GPCRs -- Stereoselective synthesis with the help of recombinant enzymes -- Nucleic acid drugs -- Recent trends in enantioseparation of chiral drugs -- Affinity chromatography -- NMR-based drug discovery -- 13C- and 15N-Isotopic labeling of proteins -- Antibody fragments as crystallization enhancers -- Pharmacogenetics: the effect of inherited henetic variation on drug disposition and drug response -- Pharmacogenomics of bioavailability and elimination -- Toxicogenomics: integration of new molecular biological tools in toxicology.

Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action.

ISBN: 3527304312 (bound) :NT$5416

LCCN: 2004351376

Nat. Bib. Agency Control No.: 967956404Subjects--Topical Terms:

500567
Molecular biology.

LC Class. No.: RM301.65 / M62 2003

Molecular biology in medicinal chemistry /
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440 0 $a Methods and principles in medicinal chemistry ; $v v. 21
504 $a Includes bibliographical references and index.
505 0 $a Cellular assays in drug discovery -- Gene knockout models -- Reporter gene assay systems for the investigation of GPCRs -- From the human genome to new drugs: The potential of orphan GPCRs -- Stereoselective synthesis with the help of recombinant enzymes -- Nucleic acid drugs -- Recent trends in enantioseparation of chiral drugs -- Affinity chromatography -- NMR-based drug discovery -- 13C- and 15N-Isotopic labeling of proteins -- Antibody fragments as crystallization enhancers -- Pharmacogenetics: the effect of inherited henetic variation on drug disposition and drug response -- Pharmacogenomics of bioavailability and elimination -- Toxicogenomics: integration of new molecular biological tools in toxicology.
520 $a Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action.
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700 1 $a Dingermann, Theodor. $3 519595
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700 1 $a Folkers, Gerd. $3 519597
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