Biological inorganic chemistry : an ...
Crichton, Robert R.

 

  • Biological inorganic chemistry : an introduction
  • 紀錄類型: 書目-語言資料,印刷品 : 單行本
    副題名: an introduction
    作者: CrichtonRobert R.,
    其他團體作者: ScienceDirect (Online service)
    出版地: Amsterdam
    出版者: Elsevier;
    出版年: 2008.
    版本: 1st ed.
    面頁冊數: xii, 369 p.ill. (some col.) : 24 cm.;
    標題: Bioinorganic chemistry. -
    標題: Electronic books. -
    電子資源: http://www.sciencedirect.com/science/book/9780444527400
    附註: Electronic reproduction. Amsterdam : Elsevier Science & Technology, 2008.
    摘要註: The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, indivbidual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finlly molybdenum, vanadium, tungsten and chromium. The final three chapers provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment. Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on. Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject. Many colour illustrations. Enables easier visualization of molecular mechanisms Written by a single author. Ensures homgeneity of style and effective cross referencing between chapters.
    ISBN: 0444527400
    內容註: An overview of metals in biology Basic coordination chemistry for biologists Biological ligands for metal ions Structural and molecular biology for chemists An overview of intermediary metabolism and bioenergetics Methods to study metals in biological systems Metal assimilation pathways Transport, storage and homeostatis of metal ions Sodium and potassium : channels and pumps Magnesium-phosphate metabolism and photoreceptors Calcium : cellular signalling Zinc : Lewis acid and gene regulator Iron : essential for almost all life Copper : coping with dioxygen Nickel and cobalt : evolutionary relics Manganese : water splitting, oxygen atom donor Molybdenum, tungsten, vanadium and chromium Metals in brain and their role in various neurodegenerative diseases Biomineralization Metals in medicine and the environment.
    內容註: The role of metals in biology - an overview Basic coordination chemistry for biologists Structural and molecular biology for chemists Biological ligands for metal ions An overview of intermediary metabolism and bioenergetics Methods which can be used to study metals in biology Metal assimilation pathways Transport, storage and homeostasis of metal ions Sodium and potassium Calcium Magnesium Zinc Iron Copper Nickel and cobalt Manganese Molybdenum, vanadium, tungsten and chromium Metals in brain function Biomineralisation Metals in medicine and the environment Concluding remarks.
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