Eukaryotic transcription factors
Latchman, David S.

 

  • Eukaryotic transcription factors
  • 紀錄類型: 書目-語言資料,印刷品 : 單行本
    作者: LatchmanDavid S.,
    其他團體作者: ScienceDirect (Online service)
    出版地: Amsterdam
    出版者: Elsevier/Academic Press;
    出版年: 2008.
    版本: 5th ed.
    面頁冊數: xxviii, 471 p.ill. (some col.) : 26 cm.;
    標題: Genetic transcription - Regulation. -
    標題: Transcription factors. -
    標題: Electronic books. -
    標題: Eukaryotic Cells. -
    標題: Gene Expression Regulation. -
    標題: Transcription Factors. -
    標題: Transcription, Genetic. -
    電子資源: http://www.sciencedirect.com/science/book/9780123739834
    附註: Electronic reproduction. Amsterdam : Elsevier Science & Technology, 2008.
    摘要註: Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. Brand new coverage in this edition includes: * Potential of transcription factors as therapeutic targets in human disease * Importance of histone modifications * Use of genome-based sequence analysis and high-throughput methods * Applications of the chromatin immunoprecipitation (ChIP) assay * Transcriptional elongation * Regulation by post-translational modifications * Regulatory networks and bioinformatics.
    ISBN: 0123739837
    內容註: DNA sequences, transcription factors and chromatin structure; Methods for studying transcription factors; RNA polymerases and the basal transcriptional complex; Families of DNA binding transcription factors; Activation of gene expression by transcription factors; Repression of gene expression by transcription factors; Regulation of transcription factor synthesis; Regulation of transcription factor activity; Transcription factors and human disease.
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