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Eukaryotic transcription factors
~
Latchman, David S.
Eukaryotic transcription factors
Record Type:
Language materials, printed : monographic
Author:
LatchmanDavid S.,
Secondary Intellectual Responsibility:
ScienceDirect (Online service)
Place of Publication:
Amsterdam
Published:
Elsevier/Academic Press;
Year of Publication:
2008.
Edition:
5th ed.
Description:
xxviii, 471 p.ill. (some col.) : 26 cm.;
Subject:
Genetic transcription - Regulation. -
Subject:
Transcription factors. -
Subject:
Electronic books. -
Subject:
Eukaryotic Cells. -
Subject:
Gene Expression Regulation. -
Subject:
Transcription Factors. -
Subject:
Transcription, Genetic. -
Online resource:
http://www.sciencedirect.com/science/book/9780123739834
Notes:
Electronic reproduction. Amsterdam : Elsevier Science & Technology, 2008.
Summary:
Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. Brand new coverage in this edition includes: * Potential of transcription factors as therapeutic targets in human disease * Importance of histone modifications * Use of genome-based sequence analysis and high-throughput methods * Applications of the chromatin immunoprecipitation (ChIP) assay * Transcriptional elongation * Regulation by post-translational modifications * Regulatory networks and bioinformatics.
ISBN:
0123739837
Content Note:
DNA sequences, transcription factors and chromatin structure; Methods for studying transcription factors; RNA polymerases and the basal transcriptional complex; Families of DNA binding transcription factors; Activation of gene expression by transcription factors; Repression of gene expression by transcription factors; Regulation of transcription factor synthesis; Regulation of transcription factor activity; Transcription factors and human disease.
Eukaryotic transcription factors
Latchman, David S.
Eukaryotic transcription factors
/ David S. Latchman. - 5th ed.. - Amsterdam : Elsevier/Academic Press, 2008.. - xxviii, 471 p. ; ill. (some col.) ; 26 cm..
DNA sequences, transcription factors and chromatin structure; Methods for studying transcription factors; RNA polymerases and the basal transcriptional complex; Families of DNA binding transcription factors; Activation of gene expression by transcription factors; Repression of gene expression by transcription factors; Regulation of transcription factor synthesis; Regulation of transcription factor activity; Transcription factors and human disease..
Electronic reproduction. Amsterdam : Elsevier Science & Technology, 2008..
Includes bibliographical references and index..
ISBN 0123739837ISBN 9780123739834
Genetic transcription Transcription factors.Electronic books.Eukaryotic Cells.Gene Expression Regulation.Transcription Factors.Transcription, Genetic. -- Regulation.
Eukaryotic transcription factors
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Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. Brand new coverage in this edition includes: * Potential of transcription factors as therapeutic targets in human disease * Importance of histone modifications * Use of genome-based sequence analysis and high-throughput methods * Applications of the chromatin immunoprecipitation (ChIP) assay * Transcriptional elongation * Regulation by post-translational modifications * Regulatory networks and bioinformatics.
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